Immunosuppressive effect of hispidulin in allergic contact dermatitis
نویسندگان
چکیده
منابع مشابه
Allergic Contact Dermatitis Physiology
Allergic Contact Dermatitis (ACD) involves the penetration of an allergen through the skin surface where it acts as a hapten by binding to epidermal proteins and eliciting, a delayed Type IV hypersensitivity reaction 48 to 120 hours after exposure. This immunologic response involves the activation of Th1 cells with the subsequent release of cytokines resulting in the classic inflammatory reaction.
متن کاملAllergic contact dermatitis
Allergic contact dermatitis is a T cell mediated, antigen-specific inflammatory reaction of the skin due to repeated epicutaneous exposure to antigens. Immunologically it is divided into 2 phases, induction and elicitation phase. During the first phase which is clinically silent, naïve T cells are activated and differentiate into antigen-specific memory T cells. During the elicitation phase, af...
متن کاملAllergic contact dermatitis.
Allergic contact dermatitis (ACD) is a common occupational and environmental health issue. In common with other forms of allergy the disease progresses in two stages; an initial phase during which sensitization is acquired, followed later (after subsequent exposure to the same chemical allergen) by elicitation of a cutaneous inflammatory reaction. The development of skin sensitization is associ...
متن کاملAllergic contact dermatitis.
Contact dermatitis is an inflammatory skin condition induced by exposure to an environmental agent. Eczema and dermatitis are used synonymously to denote a polymorphous pattern of skin inflammation characterized at least in its acute phase by erythema, vesiculation and pruritus. Substances responsible for contact dermatitis after single or multiple exposures are non protein chemicals, i.e. hapt...
متن کاملAllergic Contact Dermatitis in Children
Contact allergy (CA), a pathologic response after (usually repeated) contact to environmental substances of low molecular weight occurring in a varying proportion of exposed persons, often results in clinical disease, allergic contact dermatitis (ACD), which can be disabling. CA is diagnosed by patch testing, a technique of controlled exposure of patients suspected to have ACD to a standardized...
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ژورنال
عنوان ژورنال: BMC Complementary and Alternative Medicine
سال: 2019
ISSN: 1472-6882
DOI: 10.1186/s12906-019-2689-z